PLA2G7 抗体 (AA 176-415)
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Quick Overview for PLA2G7 抗体 (AA 176-415) (ABIN6654171)
抗原
See all PLA2G7 (Lp-PLA2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 176-415
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纯化方法
- Antigen affinity purified
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免疫原
- Amino acids A176-N415 from the human protein were used as the immunogen for the PLA2G7 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the PLA2G7 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,ELISA (Capture): 1-5 μg/mL (human recombinant protein)
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the PLA2G7 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- PLA2G7 (Lp-PLA2) (Lipoprotein-Associated phospholipase A2 (Lp-PLA2))
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别名
- PLA2G7 / Lp-PLA2 / PAFAH
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背景
- Lipoprotein-associated phospholipase A2 (Lp-PLA2), also known as platelet-activating factor acetylhydrolase (PAF-AH), is a phospholipase A2 enzyme that in humans is encoded by the PLA2G7 gene. Lp-PLA2 is a 45-50 kDa protein of 441 amino acids. It is one of several PAF acetylhydrolases. In the blood it travels mainly with low-density lipoprotein (LDL). Less than 20 % is associated with high-density lipoprotein HDL. It is an enzyme produced by inflammatory cells and hydrolyzes oxidized phospholipids in LDL. Lp-PLA2 is platelet-activating factor (PAF) acetylhydrolase, a secreted enzyme that catalyzes the degradation of PAF to inactive products by hydrolysis of the acetyl group at the sn-2 position, producing the biologically inactive products LYSO-PAF and acetate.
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UniProt
- Q13093
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途径
- Peptide Hormone Metabolism
抗原
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