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CD2AP 抗体 (AA 253-337)

This anti-CD2AP antibody is a 小鼠 单克隆 antibody detecting CD2AP in WB, FACS 和 IHC (p). Suitable for 人.
产品编号 ABIN6654151
发货至: 中国

Quick Overview for CD2AP 抗体 (AA 253-337) (ABIN6654151)

抗原

See all CD2AP (Cd2ap) 抗体
CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD2AP antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

5F8
  • 抗原表位

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    AA 253-337

    纯化方法

    Protein G affinity

    免疫原

    Amino acids K253-K337 from the human protein were used as the immunogen for the CD2AP antibody.

    亚型

    IgG1
  • 应用备注

    Optimal dilution of the CD2AP antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,FACS: 1-3 μg/10^6 cells

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the CD2AP antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))

    别名

    CD2AP

    背景

    CD2-associated protein is a protein that in humans is encoded by the CD2AP gene. This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.

    UniProt

    Q9Y5K6
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