Betacellulin 抗体 (AA 32-111)
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Quick Overview for Betacellulin 抗体 (AA 32-111) (ABIN6654020)
抗原
See all Betacellulin (BTC) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 32-111
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纯化方法
- Antigen affinity purified
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免疫原
- Amino acids D32-Y111 from the human protein were used as the immunogen for the BTC antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the BTC antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,ELISA (Capture): 1-5 μg/mL (human recombinant protein)
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the BTC antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Betacellulin (BTC)
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别名
- BTC / Betacellulin
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背景
- Betacellulin is a protein that in humans is encoded by the BTC gene located on chromosome 4 at locus 4q13-q21. This gene encodes a member of the epidermal growth factor (EGF) family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the secreted growth factor. A secreted form and a membrane-anchored form of this protein bind to multiple different EGF receptors. This protein promotes pancreatic cell proliferation and insulin secretion, as well as retinal vascular permeability. Mutations in this gene may be associated with type 2 diabetes in human patients.
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UniProt
- P35070
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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