ADA 抗体 (AA 135-363)
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Quick Overview for ADA 抗体 (AA 135-363) (ABIN6654014)
抗原
See all ADA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 135-363
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纯化方法
- Protein G affinity
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免疫原
- Amino acids Q135-L363 from the human protein were used as the immunogen for the ADA antibody.
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亚型
- IgG2b
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anti-Adenosine Deaminase (ADA) (AA 1-363) antibody
ADA 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Deaminase (ADA) (AA 2-238) antibodyADA 适用: 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Deaminase (ADA) (AA 11-280) antibodyADA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Deaminase (ADA) (AA 1-363) antibodyADA 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Deaminase (ADA) (AA 157-343) antibodyADA 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Deaminase (ADA) (AA 1-363) antibodyADA 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4G4-1C6 unconjugated
anti-Adenosine Deaminase (ADA) (AA 287-314), (C-Term) antibodyADA 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB31396 unconjugated
anti-Adenosine Deaminase (ADA) (AA 1-363) antibodyADA 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Adenosine Deaminase (ADA) (AA 2-241) antibodyADA 适用: 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Deaminase (ADA) (AA 65-170) antibodyADA 适用: 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the ADA antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,FACS: 1-3 μg/10^6 cells
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the ADA antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- ADA (Adenosine Deaminase (ADA))
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别名
- ADA / Adenosine deaminase
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背景
- Adenosine Deaminase (also known as adenosine aminohydrolase, or ADA) is an enzyme involved in purine metabolism. Primarily, ADA in humans is involved in the development and maintenance of the immune system. However, ADA association has also been observed with epithelial cell differentiation, neurotransmission, and gestation maintenance. It has also been proposed that ADA, in addition to adenosine breakdown, stimulates release of excitatory amino acids and is necessary to the coupling of A1 adenosine receptors and heterotrimeric G proteins. Adenosine deaminase deficiency leads to pulmonary fibrosis, suggesting that chronic exposure to high levels of adenosine can exacerbate inflammation responses rather than suppressing them. It has also been recognized that adenosine deaminase protein and activity is upregulated in mouse hearts that overexpress HIF-1 alpha, which in part explains the attenuated levels of adenosine in HIF-1 alpha expressing hearts during ischemic stress.
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UniProt
- P00813
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Ribonucleoside Biosynthetic Process
抗原
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