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Hsc70 抗体

This anti-Hsc70 antibody is a 大鼠 单克隆 antibody detecting Hsc70 in WB, IHC, IP 和 ICC. Suitable for 人, 大鼠, 小鼠, 小鸡 和 哺乳动物.
产品编号 ABIN6653942
发货至: 中国

Quick Overview for Hsc70 抗体 (ABIN6653942)

抗原

See all Hsc70 (HSPA8) 抗体
Hsc70 (HSPA8) (Heat Shock 70kDa Protein 8 (HSPA8))

适用

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人, 大鼠, 小鼠, 小鸡, 哺乳动物

宿主

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大鼠

克隆类型

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单克隆

标记

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This Hsc70 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

克隆位点

1B5
  • 特异性

    Reacts with human Hsc70 (Hsp73). Cross-reacts with mouse, rat, rabbit, guinea pig, hamster, monkey, sheep, chicken, bovine, canine and porcine protein.

    纯化方法

    Purified (protein G)

    免疫原

    Hsc70 purified from sodium arsenite treated heat-resistant variants of Chinese hamster cells.

    亚型

    IgG2a
  • 应用备注

    Working dilution: Optimal dilution should be determined by the end user.
    The following are guidelines only :
    WB0.1 μg/mL IP5 μg/mL IHC5 μg/mL ICC5 μg/mL

    Positive control: HeLa Heat Shocked Cell Lysate

    限制

    仅限研究用
  • 缓冲液

    PBS pH 7.2, 0.1 mM PMSF in 50 % glycerol.

    储存液

    PMSF

    储存条件

    4 °C/-20 °C

    储存方法

    Store frozen product at or below -20°C. Thawed product may be stored for 2-4 weeks at 4°C. For optimal storage, aliquot and store at -20°C.
  • 抗原

    Hsc70 (HSPA8) (Heat Shock 70kDa Protein 8 (HSPA8))

    别名

    Hsc70 (Hsp73)

    背景

    Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes

    Heat shock cognate 71 kDa protein Heat shock 70 kDa protein 8 Lipopolysaccharide-associated protein 1, LAP-1, LPS-associated protein 1 Gene name: HSPA8, HSC70, HSP73, HSPA10

    基因ID

    3312

    UniProt

    P11142
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