MME 抗体 (AA 272-300)
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北京 101111
Quick Overview for MME 抗体 (AA 272-300) (ABIN659195)
抗原
See all MME 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 272-300
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纯化方法
- Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
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免疫原
- This MME/CD10 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 272-300 amino acids from human MME/CD10.
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亚型
- IgM
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应用备注
- WB: 1:1000~4000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- MME/CD10 Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
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有效期
- 6 months
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- MME (Membrane Metallo-Endopeptidase (MME))
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别名
- MME/CD10
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物质类
- Chemical
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背景
- This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85 % of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing. [provided by RefSeq].
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分子量
- 85514
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基因ID
- 4311
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NCBI登录号
- NP_000893, NP_009218, NP_009219, NP_009220
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UniProt
- P08473
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途径
- RTK signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
抗原
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