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MMP2 抗体

This anti-MMP2 antibody is a 小鼠 单克隆 antibody detecting MMP2 in WB 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 4+ publications.
产品编号 ABIN659015
发货至: 中国

Quick Overview for MMP2 抗体 (ABIN659015)

抗原

See all MMP2 抗体
MMP2 (Matrix Metalloproteinase 2 (MMP2))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This MMP2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

6E3F8
  • 纯化方法

    Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

    免疫原

    This MMP2 antibody is generated from mouse immunized with MMP2 recombinant protein.

    亚型

    IgG2b kappa
  • 应用备注

    WB: 1:200~1000. IHC-P: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze-thaw cycles.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Zhou, Wang, Ban, Zeng, Zhu, Li, Guan, Li: "DHRS2 inhibits cell growth and motility in esophageal squamous cell carcinoma." in: Oncogene, Vol. 37, Issue 8, pp. 1086-1094, (2018) (PubMed).

    Li, Zhou, Yang, Zhou, Tan, Yuan, Song, Chen, Zhang: "The CD147/MMP-2 signaling pathway may regulate early stage cardiac remodelling in spontaneously hypertensive rats." in: Clinical and experimental pharmacology & physiology, Vol. 43, Issue 11, pp. 1125-1133, (2017) (PubMed).

    Huang, Chiu, Chou, Su, Chen, Chai, Huang, Huang, Yuan, Lee: "Association of MMP-2 and MMP-9 expression with recurrences in primary spontaneous pneumothorax." in: The Kaohsiung journal of medical sciences, Vol. 33, Issue 1, pp. 17-23, (2017) (PubMed).

    Wang, Cao, Huang, Ke, Luo, Lin, Wang, Zhang, Wang: "EFEMP1 promotes the migration and invasion of osteosarcoma via MMP-2 with induction by AEG-1 via NF-κB signaling pathway." in: Oncotarget, Vol. 6, Issue 16, pp. 14191-208, (2016) (PubMed).

  • 抗原

    MMP2 (Matrix Metalloproteinase 2 (MMP2))

    别名

    MMP2

    背景

    Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene.

    分子量

    73882

    基因ID

    4313

    NCBI登录号

    NP_001121363, NP_004521

    UniProt

    P08253

    途径

    Activation of Innate immune Response
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