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PIM1 抗体 (C-Term)

This 兔 多克隆 anti-PIM1 antibody (Clone RB34666) specifically detects PIM1 in WB. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN657998
发货至: 中国
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Quick Overview for PIM1 抗体 (C-Term) (ABIN657998)

抗原

See all PIM1 抗体
PIM1 (Pim-1 Oncogene (PIM1))

适用

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人, 小鼠

宿主

  • 120
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克隆类型

  • 91
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多克隆

标记

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This PIM1 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB34666
  • 抗原表位

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    AA 343-372, C-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This Mouse Pim1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 343-372 amino acids from the C-terminal region of mouse Pim1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Mouse Pim1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

    有效期

    6 months
  • 抗原

    PIM1 (Pim-1 Oncogene (PIM1))

    别名

    Pim1

    背景

    Pim1 may affect the structure or silencing of chromatin by phosphorylating HP1 gamma/CBX3 (By similarity). Promotes the G1/S transition of the cell cycle via up-regulation of CDK2 activity and phosphorylation of CDKN1B, resulting in enhanced nuclear export and proteasome-dependent degradation of CDKN1B (By similarity). Also represses CDKN1B transcription by phosphorylating and inactivating the transcription factor FOXO3 (By similarity). Plays a role in signal transduction in blood cells (By similarity). Contributes to both cell proliferation and survival thus providing a selective advantage in tumorigenesis (By similarity).

    分子量

    35451

    基因ID

    18712

    UniProt

    P06803

    途径

    Glycosaminoglycan Metabolic Process
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