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MANF 抗体 (AA 11-60)

This 兔 多克隆 antibody specifically detects MANF in WB, IHC, ELISA 和 IF. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN6579649
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MANF 抗体 (AA 11-60) (ABIN6579649)

抗原

See all MANF 抗体
MANF (Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF))

适用

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人, 小鼠, 大鼠

宿主

  • 38
  • 10
  • 1
兔

克隆类型

  • 41
  • 8
多克隆

标记

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This MANF antibody is un-conjugated

应用范围

  • 36
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  • 10
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  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 7
    • 4
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    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    • 1
    AA 11-60

    原理

    ARP Antibody

    特异性

    ARP Polyclonal Antibody detects endogenous levels of ARP protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized peptide derived from the Internal region of human MANF. AA range:11-60

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    MANF (Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF))

    别名

    MANF

    背景

    Synonyms: MANF, ARMET, ARP, Mesencephalic astrocyte-derived neurotrophic factor, Arginine-rich protein, Protein ARMET

    Background: The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and results in cell proliferation. Activity of this protein is important in promoting the survival of dopaminergic neurons. The presence of polymorphisms in the N-terminal arginine-rich region, including a specific mutation that changes an ATG start codon to AGG, have been reported in a variety of solid tumors, however, these polymorphisms were later shown to exist in normal tissues and are thus no longer thought to be tumor-related. [provided by RefSeq, Apr 2014],

    Gene Name: MANF

    Protein Name: Mesencephalic astrocyte-derived neurotrophic factor

    分子量

    20 kDa

    基因ID

    7873

    OMIM

    601916

    UniProt

    P55145
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