IL-24 抗体 (AA 131-180)
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北京 101111
Quick Overview for IL-24 抗体 (AA 131-180) (ABIN6579604)
抗原
See all IL-24 (IL24) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 131-180
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原理
- MDA-7 Antibody
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特异性
- MDA-7 Polyclonal Antibody detects endogenous levels of MDA-7 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from the Internal region of human IL24. AA range:131-180
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- IL-24 (IL24) (Interleukin 24 (IL24))
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别名
- IL24
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背景
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Synonyms: IL24, MDA7, ST16, Interleukin-24, IL-24, Melanoma differentiation-associated gene 7 protein, MDA-7, Suppression of tumorigenicity 16 protein
Background: This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells.The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27 kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008],
Gene Name: IL24
Protein Name: Interleukin-24
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分子量
- 23 kDa
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基因ID
- 11009
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OMIM
- 604136
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UniProt
- Q13007
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途径
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Autophagy
抗原
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