Amphiregulin 抗体 (AA 91-140)
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北京 101111
Quick Overview for Amphiregulin 抗体 (AA 91-140) (ABIN6579595)
抗原
See all Amphiregulin (AREG) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 91-140
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原理
- Amphiregulin Antibody
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特异性
- Amphiregulin Polyclonal Antibody detects endogenous levels of Amphiregulin protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from the Internal region of human AREG/AREGB. AA range:91-140
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Amphiregulin (AREG)
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别名
- AREG/AREGB
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背景
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Synonyms: AREG, SDGF, AREGB, Amphiregulin, AR, Colorectum cell-derived growth factor, CRDGF
Background: The protein encoded byThis gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions. [provided by RefSeq, Apr 2014],
Gene Name: AREG/AREGB
Protein Name: Amphiregulin
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分子量
- 27 kDa
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基因ID
- 374, 727738
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OMIM
- 104640
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UniProt
- P15514
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途径
- RTK signaling, EGFR Signaling Pathway
抗原
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