Betacellulin 抗体 (AA 21-70)
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北京 101111
Quick Overview for Betacellulin 抗体 (AA 21-70) (ABIN6579592)
抗原
See all Betacellulin (BTC) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 21-70
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原理
- Probetacellulin Antibody
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特异性
- Probetacellulin Polyclonal Antibody detects endogenous levels of Probetacellulin protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from the Internal region of human BTC. AA range:21-70
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亚型
- IgG
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应用备注
- WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Betacellulin (BTC)
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别名
- BTC
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背景
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Synonyms: BTC, Probetacellulin
Background: This gene encodes a member of the epidermal growth factor (EGF) family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the secreted growth factor. A secreted form and a membrane-anchored form of this protein bind to multiple different EGF receptors. This protein promotes pancreatic cell proliferation and insulin secretion, as well as retinal vascular permeability. Mutations in this gene may be associated with type 2 diabetes in human patients. [provided by RefSeq, Nov 2015],
Gene Name: BTC
Protein Name: Probetacellulin
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分子量
- 19 kDa
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基因ID
- 685
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OMIM
- 600345
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UniProt
- P35070
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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