CD276 抗体 (AA 271-320)
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Quick Overview for CD276 抗体 (AA 271-320) (ABIN6579576)
抗原
See all CD276 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 271-320
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原理
- CD276 Antibody
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特异性
- CD276 Polyclonal Antibody detects endogenous levels of CD276 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from the Internal region of human CD276. AA range:271-320
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- CD276
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别名
- CD276
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背景
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Synonyms: CD276; B7H3; PSEC0249; CD276 antigen; 4Ig-B7-H3; B7 homolog 3; B7-H3; Costimulatory molecule; CD276
Background: The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],
Gene Name: CD276
Protein Name: CD276 antigen
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分子量
- 57 kDa
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基因ID
- 80381
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OMIM
- 605715
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UniProt
- Q5ZPR3
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途径
- Cancer Immune Checkpoints
抗原
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