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MCM3 抗体 (N-Term)

The 兔 多克隆 anti-MCM3 antibody is suitable to detect MCM3 in samples from 人. It has been validated for WB.
产品编号 ABIN657947
发货至: 中国
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Quick Overview for MCM3 抗体 (N-Term) (ABIN657947)

抗原

See all MCM3 抗体
MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))

适用

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人

宿主

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兔

克隆类型

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多克隆

标记

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This MCM3 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB34044
  • 抗原表位

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    AA 36-64, N-Term

    预测反应

    B, M

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This MCM3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-64 amino acids from the N-terminal region of human MCM3.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    MCM3 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

    有效期

    6 months
  • 抗原

    MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))

    别名

    MCM3

    背景

    The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. [provided by RefSeq].

    分子量

    90981

    基因ID

    4172

    NCBI登录号

    NP_001257401, NP_002379

    UniProt

    P25205

    途径

    DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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