CR1L 抗体 (AA 300-350)
Our Local Distributor
北京 101111
Quick Overview for CR1L 抗体 (AA 300-350) (ABIN6579446)
抗原
See all CR1L 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 300-350
-
原理
- CD35 Antibody
-
特异性
- CD35 Polyclonal Antibody detects endogenous levels of CD35
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- The antiserum was produced against synthesized peptide derived from the Internal region of human CR1/CR1L. AA range:300-350 & 740-790
-
亚型
- IgG
-
-
anti-Complement Component (3b/4b) Receptor 1-Like (CR1L) (AA 51-150) antibody
CR1L 适用: 人 WB, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Complement Component (3b/4b) Receptor 1-Like (CR1L) (AA 57-106) antibodyCR1L 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB 1:500-2000, ELISA 1:10000-20000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- CR1L (Complement Component (3b/4b) Receptor 1-Like (CR1L))
-
别名
- CR1/CR1L
-
背景
-
Synonyms: complement component (3b/4b) receptor 1/2 (Knops blood group)
Background: This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus and sarcoidosis. Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria. Alternate allele-specific splice variants
Protein Name: CD35
-
分子量
- '220 kDa
-
基因ID
- 1378, 1379
-
UniProt
- P17927
-
途径
- Complement System
抗原
-
