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PITX2 抗体 (N-Term)

This anti-PITX2 antibody is a 兔 多克隆 antibody detecting PITX2 in WB. Suitable for 人.
产品编号 ABIN657942
发货至: 中国

Quick Overview for PITX2 抗体 (N-Term) (ABIN657942)

抗原

See all PITX2 抗体
PITX2 (Paired-Like Homeodomain 2 (PITX2))

适用

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宿主

  • 43
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克隆类型

  • 46
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多克隆

标记

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This PITX2 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB34027
  • 抗原表位

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    AA 42-71, N-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This PITX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-71 amino acids from the N-terminal region of human PITX2.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    PITX2 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

    有效期

    6 months
  • 抗原

    PITX2 (Paired-Like Homeodomain 2 (PITX2))

    别名

    PITX2

    背景

    This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. The encoded protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. This protein plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this gene are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development. Alternatively spliced transcript variants encoding distinct isoforms have been described.

    分子量

    35370

    基因ID

    5308

    NCBI登录号

    NP_000316, NP_001191326, NP_001191327, NP_001191328, NP_700475, NP_700476

    UniProt

    Q99697

    途径

    Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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