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PITX2 抗体 (N-Term)

There is 1 publication for this product available. The 兔 多克隆 anti-PITX2 antibody is suitable to detect PITX2 in samples from 人, 大鼠, 小鼠, Pig, 兔, Cow 和 犬. It has been validated for WB 和 IHC.
产品编号 ABIN2776373
发货至: 中国
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Quick Overview for PITX2 抗体 (N-Term) (ABIN2776373)

抗原

See all PITX2 抗体
PITX2 (Paired-Like Homeodomain 2 (PITX2))

适用

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人, 大鼠, 小鼠, Pig, 兔, Cow, 犬

宿主

  • 55
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兔

克隆类型

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多克隆

标记

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This PITX2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    原理

    PITX2 Antibody - N-terminal region

    序列

    SAVSSSSCHH PQPLAMASVL APGQPRSLDS SKHRLEVHTI SDTSSPEAAE

    预测反应

    Cow: 100%, Dog: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 93%

    产品特性

    This is a rabbit polyclonal antibody against PITX2. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human PITX2
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8107583

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • Hatou, Yoshida, Higa, Miyashita, Inagaki, Okano, Tsubota, Shimmura: "Functional corneal endothelium derived from corneal stroma stem cells of neural crest origin by retinoic acid and Wnt/?-catenin signaling." in: Stem cells and development, Vol. 22, Issue 5, pp. 828-39, (2013) (PubMed).

  • 抗原

    PITX2 (Paired-Like Homeodomain 2 (PITX2))

    别名

    PITX2

    背景

    Background Information: The PITX2 gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. This protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. Mutations in PITX2 are associated with Axenfeld-Rieger syndrome (ARS), iridogoniodysgenesis syndrome (IGDS), and sporadic cases of Peters anomaly. This protein is involved in the development of the eye, tooth and abdominal organs. It also acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin.

    Gene Name: Paired-like homeodomain 2

    Alternative Symbols: RS, RGS, ARP1, Brx1, IDG2, IGDS, IHG2, PTX2, RIEG, ASGD4, IGDS2, IRID2, Otlx2, RIEG1

    Protein Name: Pituitary homeobox 2

    分子量

    36kDa

    基因ID

    5308

    NCBI登录号

    NP_000316

    UniProt

    Q99697

    途径

    Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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