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MCM6 抗体 (AA 331-380)

The 兔 多克隆 anti-MCM6 antibody (ABIN6579413) specifically detects MCM6 in IHC 和 WB. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN6579413
发货至: 中国
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Quick Overview for MCM6 抗体 (AA 331-380) (ABIN6579413)

抗原

See all MCM6 抗体
MCM6 (Minichromosome Maintenance Complex Component 6 (MCM6))

适用

  • 143
  • 85
  • 80
  • 10
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  • 7
  • 7
  • 4
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 80
  • 59
  • 4
兔

克隆类型

  • 79
  • 64
多克隆

标记

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  • 9
  • 6
  • 6
  • 6
  • 6
  • 5
  • 5
  • 5
  • 5
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MCM6 antibody is un-conjugated

应用范围

  • 127
  • 120
  • 84
  • 66
  • 64
  • 35
  • 22
  • 20
  • 11
  • 11
  • 3
  • 1
  • 1
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Immunohistochemistry (IHC), Western Blotting (WB)
  • 抗原表位

    • 52
    • 16
    • 13
    • 13
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 331-380

    原理

    MCM6 Antibody

    特异性

    MCM6 Polyclonal Antibody detects endogenous levels of MCM6 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized peptide derived from the Internal region of human MCM6. AA range:331-380

    亚型

    IgG
  • 应用备注

    WB 1:500-2000,IHC 1:50-300

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    MCM6 (Minichromosome Maintenance Complex Component 6 (MCM6))

    别名

    MCM6

    背景

    Synonyms: MCM6, DNA replication licensing factor MCM6, p105MCM

    Background: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication. Single nucleotide polymorphisms in the intron regions of this gene are associated with differential transcriptional activation of the promoter of the neighboring lactase gene and, thereby, i

    Gene Name: MCM6

    Protein Name: DNA replication licensing factor MCM6

    分子量

    92 kDa

    基因ID

    4175

    UniProt

    Q14566

    途径

    DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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