DKK1 抗体 (AA 181-230)
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北京 101111
Quick Overview for DKK1 抗体 (AA 181-230) (ABIN6579347)
抗原
See all DKK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 181-230
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原理
- Dkk-1 Antibody
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特异性
- Dkk-1 Polyclonal Antibody detects endogenous levels of Dkk-1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from the C-terminal region of human DKK1. AA range:181-230
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- DKK1 (Dickkopf Homolog 1 (DKK1))
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别名
- DKK1
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背景
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Synonyms: DKK1, Dickkopf-related protein 1, Dickkopf-1, Dkk-1, hDkk-1, SK
Background: This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. [provided by RefSeq, Jul 2008],
Gene Name: DKK1
Protein Name: Dickkopf-related protein 1
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分子量
- 28 kDa
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基因ID
- 22943
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OMIM
- 605189
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UniProt
- O94907
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途径
- WNT signaling, Regulation of Muscle Cell Differentiation, Positive Regulation of fat Cell Differentiation
抗原
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