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MCM7 抗体 (AA 491-540)

This 兔 多克隆 antibody specifically detects MCM7 in WB, IHC, IF 和 ELISA. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN6579314
发货至: 中国
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MCM7 抗体 (AA 491-540) (ABIN6579314)

抗原

See all MCM7 抗体
MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))

适用

  • 202
  • 58
  • 48
  • 13
  • 11
  • 10
  • 9
  • 9
  • 4
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 136
  • 64
  • 2
兔

克隆类型

  • 105
  • 97
多克隆

标记

  • 94
  • 12
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
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  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This MCM7 antibody is un-conjugated

应用范围

  • 164
  • 107
  • 85
  • 68
  • 60
  • 24
  • 21
  • 18
  • 14
  • 13
  • 13
  • 3
  • 2
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  • 1
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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA
  • 抗原表位

    • 51
    • 25
    • 15
    • 15
    • 9
    • 9
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 491-540

    原理

    MCM7 Antibody

    特异性

    MCM7 Polyclonal Antibody detects endogenous levels of MCM7 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized peptide derived from the Internal region of human MCM7. AA range:491-540

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))

    别名

    MCM7

    背景

    Synonyms: MCM7, CDC47, MCM2, DNA replication licensing factor MCM7, CDC47 homolog, P1.1-MCM3

    Background: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008],

    Gene Name: MCM7

    Protein Name: DNA replication licensing factor MCM7

    分子量

    81 kDa

    基因ID

    4176

    OMIM

    600592

    UniProt

    P33993

    途径

    DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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