ANGPTL4 抗体 (AA 301-350)
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北京 101111
Quick Overview for ANGPTL4 抗体 (AA 301-350) (ABIN6579282)
抗原
See all ANGPTL4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 301-350
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原理
- Angptl4 Antibody
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特异性
- Angptl4 Polyclonal Antibody detects endogenous levels of Angptl4 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from the Internal region of human ANGPTL4. AA range:301-350
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亚型
- IgG
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应用备注
- IHC: 100-300.WB 1:500 - 1:2000. ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))
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别名
- ANGPTL4
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背景
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Synonyms: ANGPTL4, ARP4, HFARP, PGAR, PP1158, PSEC0166, Angiopoietin-related protein 4, Angiopoietin-like protein 4, Hepatic fibrinogen/angiopoietin-related protein, HFARP
Background: This gene encodes a glycosylated, secreted protein containing a C-terminal fibrinogen domain. The encoded protein is induced by peroxisome proliferation activators and functions as a serum hormone that regulates glucose homeostasis, lipid metabolism, and insulin sensitivity. This protein can also act as an apoptosis survival factor for vascular endothelial cells and can prevent metastasis by inhibiting vascular growth and tumor cell invasion. The C-terminal domain may be proteolytically-cleaved from the full-length secreted protein. Decreased expression of this gene has been associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4. [provided by RefSeq, Sep 2013],
Gene Name: ANGPTL4
Protein Name: Angiopoietin-related protein 4
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分子量
- 45 kDa
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基因ID
- 51129
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OMIM
- 605910
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UniProt
- Q9BY76
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途径
- Regulation of Lipid Metabolism by PPARalpha
抗原
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