APOA1 抗体 (AA 81-130)
Our Local Distributor
北京 101111
Quick Overview for APOA1 抗体 (AA 81-130) (ABIN6579270)
抗原
See all APOA1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 81-130
-
原理
- ApoA-I Antibody
-
特异性
- ApoA-I Polyclonal Antibody detects endogenous levels of ApoA-I protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- The antiserum was produced against synthesized peptide derived from the Internal region of human APOA1. AA range:81-130
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- APOA1 (Apolipoprotein A-I (APOA1))
-
别名
- APOA1
-
背景
-
Synonyms: APOA1, Apolipoprotein A-I, Apo-AI, ApoA-I, Apolipoprotein A1
Background: This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The encoded preproprotein is proteolytically processed to generate the mature protein, which promotes cholesterol efflux from tissues to the liver for excretion, and is a cofactor for lecithin cholesterolacyltransferase (LCAT), an enzyme responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein. [provided by RefSeq, Dec 2015],
Gene Name: APOA1
Protein Name: Apolipoprotein A-I
-
分子量
- 30 kDa
-
基因ID
- 335
-
OMIM
- 107680
-
UniProt
- P02647
-
途径
- Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response, Lipid Metabolism
抗原
-