FGF2 抗体 (AA 151-200)
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Quick Overview for FGF2 抗体 (AA 151-200) (ABIN6579260)
抗原
See all FGF2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 151-200
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原理
- FGF-2 Antibody
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特异性
- FGF-2 Polyclonal Antibody detects endogenous levels of FGF-2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from the Internal region of human FGF2. AA range:151-200
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))
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别名
- FGF2
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背景
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Synonyms: FGF2, FGFB, Fibroblast growth factor 2, FGF-2, Basic fibroblast growth factor, bFGF, Heparin-binding growth factor 2, HBGF-2
Background: The protein encoded byThis gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. [provided by RefSeq, Jul 2008],
Gene Name: FGF2
Protein Name: Fibroblast growth factor 2
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分子量
- 30 kDa
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基因ID
- 2247
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OMIM
- 134920
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UniProt
- P09038
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, C21-Steroid Hormone Metabolic Process, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Protein targeting to Nucleus, S100 Proteins
抗原
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