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K-RAS 抗体 (AA 150-189)

This 兔 多克隆 antibody specifically detects K-RAS in WB, ELISA, IHC 和 IF. It exhibits reactivity toward 人, 大鼠 和 小鼠.
产品编号 ABIN6579257
发货至: 中国
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Quick Overview for K-RAS 抗体 (AA 150-189) (ABIN6579257)

抗原

See all K-RAS (KRAS) 抗体
K-RAS (KRAS) (GTPase Kras (KRAS))

适用

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人, 大鼠, 小鼠

宿主

  • 78
  • 18
兔

克隆类型

  • 71
  • 24
  • 1
多克隆

标记

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This K-RAS antibody is un-conjugated

应用范围

  • 74
  • 34
  • 24
  • 14
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  • 7
  • 5
  • 3
  • 3
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 16
    • 10
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    • 5
    • 5
    • 3
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    • 1
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    AA 150-189

    原理

    K-Ras Antibody

    特异性

    K-Ras Polyclonal Antibody detects endogenous levels of v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized peptide derived from the C-terminal region of human KRAS. AA range:150-189

    亚型

    IgG
  • 应用备注

    IHC: 100-300.WB 1:500 - 1:2000. ELISA: 1:10000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    K-RAS (KRAS) (GTPase Kras (KRAS))

    别名

    KRAS

    背景

    Synonyms: GTPase KRas (K-Ras 2, Ki-Ras, c-K-ras, c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]

    Background: This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008],

    Gene Name: KRAS

    Protein Name: v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog

    分子量

    21 kDa

    基因ID

    3845

    OMIM

    190070

    UniProt

    P01116
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