K-RAS 抗体 (AA 150-189)
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北京 101111
Quick Overview for K-RAS 抗体 (AA 150-189) (ABIN6579257)
抗原
See all K-RAS (KRAS) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 150-189
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原理
- K-Ras Antibody
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特异性
- K-Ras Polyclonal Antibody detects endogenous levels of v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from the C-terminal region of human KRAS. AA range:150-189
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亚型
- IgG
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应用备注
- IHC: 100-300.WB 1:500 - 1:2000. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- K-RAS (KRAS) (GTPase Kras (KRAS))
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别名
- KRAS
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背景
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Synonyms: GTPase KRas (K-Ras 2, Ki-Ras, c-K-ras, c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Background: This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008],
Gene Name: KRAS
Protein Name: v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
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分子量
- 21 kDa
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基因ID
- 3845
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OMIM
- 190070
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UniProt
- P01116
抗原
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