MME 抗体 (AA 491-540)
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Quick Overview for MME 抗体 (AA 491-540) (ABIN6579217)
抗原
See all MME 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 491-540
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原理
- CD10 Antibody
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特异性
- CD10 Polyclonal Antibody detects endogenous levels of CD10 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from the Internal region of human MME. AA range:491-540
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亚型
- IgG
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anti-Membrane Metallo-Endopeptidase (MME) (AA 52-246) antibody
MME 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 7D4B1 unconjugated
anti-Membrane Metallo-Endopeptidase (MME) (AA 52-352) antibodyMME 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Membrane Metallo-Endopeptidase (MME) (AA 501-600) antibodyMME 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Membrane Metallo-Endopeptidase (MME) (AA 297-483) antibodyMME 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal MME-1870 unconjugated
anti-Membrane Metallo-Endopeptidase (MME) (AA 382-538) antibodyMME 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Membrane Metallo-Endopeptidase (MME) antibody (PE)MME 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-78 PE
anti-Membrane Metallo-Endopeptidase (MME) (AA 297-483) antibodyMME 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal MME-1892 unconjugated
anti-Membrane Metallo-Endopeptidase (MME) (AA 549-750) antibodyMME 适用: 人 IHC, FACS, ELISA 宿主: 小鼠 Monoclonal 3G6B11 unconjugated
anti-Membrane Metallo-Endopeptidase (MME) (AA 549-750) antibodyMME 适用: 人 WB, FACS, ELISA 宿主: 小鼠 Monoclonal 6G12E12 unconjugated
anti-Membrane Metallo-Endopeptidase (MME) (AA 286-428) antibodyMME 适用: 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- MME (Membrane Metallo-Endopeptidase (MME))
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别名
- MME
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物质类
- Chemical
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背景
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Synonyms: MME; EPN; Neprilysin; Atriopeptidase; Common acute lymphocytic leukemia antigen; CALLA; Enkephalinase; Neutral endopeptidase 24.11; NEP; Neutral endopeptidase; Skin fibroblast elastase; SFE; CD10
Background: This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this
Gene Name: MME
Protein Name: Neprilysin
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分子量
- 85 kDa
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基因ID
- 4311
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OMIM
- 120520
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UniProt
- P08473
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途径
- RTK signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
抗原
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