Laminin beta 1 抗体 (C-Term)
Quick Overview for Laminin beta 1 抗体 (C-Term) (ABIN657904)
抗原
See all Laminin beta 1 (LAMB1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 1691-1720, C-Term
-
纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
-
免疫原
- This LAMB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1691-1720 amino acids from the C-terminal region of human LAMB1.
-
亚型
- Ig Fraction
-
-
anti-Laminin, beta 1 (LAMB1) antibody
LAMB1 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Laminin, beta 1 (LAMB1) (AA 1053-1258) antibodyLAMB1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Laminin, beta 1 (LAMB1) (C-Term) antibodyLAMB1 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Laminin, beta 1 (LAMB1) (C-Term) antibodyLAMB1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Laminin, beta 1 (LAMB1) (C-Term) antibodyLAMB1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Laminin, beta 1 (LAMB1) (AA 31-270) antibodyLAMB1 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 2D9G5 unconjugated
anti-Laminin, beta 1 (LAMB1) (AA 1-1786) antibodyLAMB1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Laminin, beta 1 (LAMB1) (Middle Region) antibodyLAMB1 适用: 人, 小鼠, 大鼠, 兔, 犬, 豚鼠, 马, Cow, Pig, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
anti-Laminin, beta 1 (LAMB1) (AA 1721-1770) antibodyLAMB1 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Laminin, beta 1 (LAMB1) (AA 523-661) antibodyLAMB1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB: 1:1000. IHC-P: 1:10~50
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- LAMB1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
-
有效期
- 6 months
-
-
- Laminin beta 1 (LAMB1) (Laminin, beta 1 (LAMB1))
-
别名
- LAMB1
-
背景
- Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. The biological functions of the different chains and trimer molecules are largely unknown, but some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo. This gene encodes the beta chain isoform laminin, beta 1. The beta 1 chain has 7 structurally distinct domains which it shares with other beta chain isomers. The C-terminal helical region containing domains I and II are separated by domain alpha, domains III and V contain several EGF-like repeats, and domains IV and VI have a globular conformation. Laminin, beta 1 is expressed in most tissues that produce basement membranes, and is one of the 3 chains constituting laminin 1, the first laminin isolated from Engelbreth-Holm-Swarm (EHS) tumor. A sequence in the beta 1 chain that is involved in cell attachment, chemotaxis, and binding to the laminin receptor was identified and shown to have the capacity to inhibit metastasis.
-
分子量
- 198038
-
基因ID
- 3912
-
NCBI登录号
- NP_002282
-
UniProt
- P07942
抗原
-
