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RANGAP1 抗体 (N-Term)

This anti-RANGAP1 antibody is a 兔 多克隆 antibody detecting RANGAP1 in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN657698
发货至: 中国
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Quick Overview for RANGAP1 抗体 (N-Term) (ABIN657698)

抗原

See all RANGAP1 抗体
RANGAP1 (Ran GTPase Activating Protein 1 (RANGAP1))

适用

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宿主

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克隆类型

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多克隆

标记

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This RANGAP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB33892
  • 抗原表位

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    AA 20-49, N-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This RANGAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-49 amino acids from the N-terminal region of human RANGAP1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    RANGAP1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

    有效期

    6 months
  • 抗原

    RANGAP1 (Ran GTPase Activating Protein 1 (RANGAP1))

    别名

    RANGAP1

    背景

    RanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1,000-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the active, GTP-bound state. The RANGAP1 gene encodes a 587-amino acid polypeptide. The sequence is unrelated to that of GTPase activators for other RAS-related proteins, but is 88 % identical to Fug1, the murine homolog of yeast Rna1p. RanGAP1 and RCC1 control RAN-dependent transport between the nucleus and cytoplasm. RanGAP1 is a key regulator of the RAN GTP/GDP cycle.

    分子量

    63542

    基因ID

    5905

    NCBI登录号

    NP_001265580, NP_002874

    UniProt

    P46060

    途径

    M Phase, Protein targeting to Nucleus
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