RANGAP1 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for RANGAP1 抗体 (N-Term) (ABIN657698)
抗原
See all RANGAP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 20-49, N-Term
-
纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
-
免疫原
- This RANGAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-49 amino acids from the N-terminal region of human RANGAP1.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- RANGAP1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
-
有效期
- 6 months
-
-
- RANGAP1 (Ran GTPase Activating Protein 1 (RANGAP1))
-
别名
- RANGAP1
-
背景
- RanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1,000-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the active, GTP-bound state. The RANGAP1 gene encodes a 587-amino acid polypeptide. The sequence is unrelated to that of GTPase activators for other RAS-related proteins, but is 88 % identical to Fug1, the murine homolog of yeast Rna1p. RanGAP1 and RCC1 control RAN-dependent transport between the nucleus and cytoplasm. RanGAP1 is a key regulator of the RAN GTP/GDP cycle.
-
分子量
- 63542
-
基因ID
- 5905
-
NCBI登录号
- NP_001265580, NP_002874
-
UniProt
- P46060
-
途径
- M Phase, Protein targeting to Nucleus
抗原
-