PPP4C 抗体 (AA 160-189)
Quick Overview for PPP4C 抗体 (AA 160-189) (ABIN657678)
抗原
See all PPP4C 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 160-189
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预测反应
- Zf, B, M, Rb, Rat, X
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This PPP4C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-189 amino acids from the Central region of human PPP4C.
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亚型
- Ig Fraction
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anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) (AA 1-307) antibody
PPP4C 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) (AA 265-307) antibodyPPP4C 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) (C-Term) antibodyVerified PPP4C 适用: 人, 大鼠 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) (AA 1-307) antibodyPPP4C 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) (C-Term) antibodyPPP4C 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) (AA 1-307) antibodyPPP4C 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E8 unconjugated
anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) antibodyPPP4C 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) (AA 218-307) antibodyPPP4C 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) (AA 1-307) antibodyPPP4C 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) (C-Term) antibodyPPP4C 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 马, 豚鼠, 斑马鱼, Bat, Hamster, 猴, 非洲爪蟾, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. IHC-P: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- PPP4C Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
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有效期
- 6 months
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- PPP4C (Protein Phosphatase 4, Catalytic Subunit (PPP4C))
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别名
- PPP4C
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背景
- Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on Ser-140 (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair. Dephosphorylates NDEL1 at CDK1 phosphorylation sites and negatively regulates CDK1 activity in interphase (By similarity).
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分子量
- 35080
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基因ID
- 5531
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NCBI登录号
- NP_002711
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UniProt
- P60510
抗原
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