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- 抗原 See all PPP4C 抗体
- PPP4C (Protein Phosphatase 4, Catalytic Subunit (PPP4C))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PPP4C antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- 特异性
- PPP4C Antibody detects endogenous levels of total PPP4C.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human PPP4C, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product PPP4C Primary Antibody
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anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) (AA 1-307) antibody
PPP4C 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) antibodyPPP4C 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) (AA 265-307) antibodyPPP4C 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) (C-Term) antibodyVerified PPP4C 适用: 人, 大鼠 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) (AA 1-307) antibodyPPP4C 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) (AA 1-307) antibodyPPP4C 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E8 unconjugated
anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) antibodyPPP4C 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) (AA 218-307) antibodyPPP4C 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) (AA 1-307) antibodyPPP4C 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) antibodyPPP4C 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2 unconjugated
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- PPP4C (Protein Phosphatase 4, Catalytic Subunit (PPP4C))
- 别名
- PPP4C (PPP4C 产品)
- 别名
- pp4 antibody, ppx antibody, pp4c antibody, pph3 antibody, MGC75928 antibody, PP4C-A antibody, gc:56413 antibody, ppp4c antibody, wu:fd05e08 antibody, zgc:56413 antibody, PP4 antibody, PP4C antibody, PPH3 antibody, PPP4 antibody, PPX antibody, 1110002D08Rik antibody, AU016079 antibody, Ppx antibody, protein phosphatase 4 catalytic subunit antibody, protein phosphatase 4, catalytic subunit a antibody, protein phosphatase 4, catalytic subunit antibody, protein phosphatase 4 catalytic subunit S homeolog antibody, ppp4c antibody, ppp4ca antibody, PPP4C antibody, Ppp4c antibody, ppp4c.S antibody
- 背景
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Description: Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on Ser-140 (gamma-H2AFX) generated during DNA replication and required for DNA double strand break repair. Dephosphorylates NDEL1 at CDK1 phosphorylation sites and negatively regulates CDK1 activity in interphase (By similarity). In response to DNA damage, catalyzes RPA2 dephosphorylation, an essential step for DNA repair since it allows the efficient RPA2-mediated recruitment of RAD51 to chromatin.
Gene: PPP4C
- 分子量
- 35kDa
- 基因ID
- 5531
- UniProt
- P60510
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