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SF3B1 抗体 (N-Term)

This anti-SF3B1 antibody is a 兔 多克隆 antibody detecting SF3B1 in WB 和 IHC (p). Suitable for 人 和 小鼠.
产品编号 ABIN657676
发货至: 中国

Quick Overview for SF3B1 抗体 (N-Term) (ABIN657676)

抗原

See all SF3B1 抗体
SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))

适用

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人, 小鼠

宿主

  • 57
  • 4

克隆类型

  • 42
  • 19
多克隆

标记

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This SF3B1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB33758
  • 抗原表位

    • 15
    • 5
    • 5
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    • 2
    • 2
    • 2
    • 1
    • 1
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    AA 374-402, N-Term

    预测反应

    X

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This SF3B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-402 amino acids from the N-terminal region of human SF3B1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. WB: 1:2000. IHC-P: 1:10~50. IHC-P: 1:25

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    SF3B1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

    有效期

    6 months
  • 抗原

    SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))

    别名

    SF3B1

    背景

    This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq].

    分子量

    145830

    基因ID

    23451

    NCBI登录号

    NP_036565

    UniProt

    O75533

    途径

    Chromatin Binding
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