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IL-13 抗体 (C-Term)

This 兔 多克隆 anti-IL-13 antibody (Clone RB33718) specifically detects IL-13 in WB, IF 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN657659
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for IL-13 抗体 (C-Term) (ABIN657659)

抗原

See all IL-13 (IL13) 抗体
IL-13 (IL13) (Interleukin 13 (IL13))

适用

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宿主

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克隆类型

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多克隆

标记

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This IL-13 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB33718
  • 抗原表位

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    AA 118-146, C-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This IL13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-146 amino acids from the C-terminal region of human IL13.

    亚型

    Ig Fraction
  • 应用备注

    IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    IL13 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

    有效期

    6 months
  • 抗原

    IL-13 (IL13) (Interleukin 13 (IL13))

    别名

    IL13

    背景

    This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq].

    分子量

    15816

    基因ID

    3596

    NCBI登录号

    NP_002179

    UniProt

    P35225

    途径

    JAK/STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport
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