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Cortactin 抗体 (AA 273-302)

This anti-Cortactin antibody is a 兔 多克隆 antibody detecting Cortactin in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN657649
发货至: 中国

Quick Overview for Cortactin 抗体 (AA 273-302) (ABIN657649)

抗原

See all Cortactin (CTTN) 抗体
Cortactin (CTTN)

适用

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宿主

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克隆类型

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多克隆

标记

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This Cortactin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB33698
  • 抗原表位

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    AA 273-302

    预测反应

    C

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This CTTN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273-302 amino acids from the Central region of human CTTN.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    CTTN Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

    有效期

    6 months
  • 抗原

    Cortactin (CTTN)

    别名

    CTTN

    背景

    This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.

    分子量

    61586

    基因ID

    2017

    NCBI登录号

    NP_001171669, NP_005222, NP_612632

    UniProt

    Q14247

    途径

    MAPK Pathway
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