Cortactin 抗体 (AA 273-302)
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北京 101111
Quick Overview for Cortactin 抗体 (AA 273-302) (ABIN657649)
抗原
See all Cortactin (CTTN) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 273-302
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预测反应
- C
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This CTTN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273-302 amino acids from the Central region of human CTTN.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- CTTN Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
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有效期
- 6 months
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- Cortactin (CTTN)
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别名
- CTTN
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背景
- This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.
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分子量
- 61586
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基因ID
- 2017
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NCBI登录号
- NP_001171669, NP_005222, NP_612632
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UniProt
- Q14247
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途径
- MAPK Pathway
抗原
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