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MMP16 抗体 (C-Term)

This anti-MMP16 antibody is a 兔 多克隆 antibody detecting MMP16 in WB 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN657636
发货至: 中国

Quick Overview for MMP16 抗体 (C-Term) (ABIN657636)

抗原

See all MMP16 抗体
MMP16 (Matrix Metallopeptidase 16 (Membrane-inserted) (MMP16))

适用

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宿主

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克隆类型

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多克隆

标记

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This MMP16 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB33657
  • 抗原表位

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    AA 519-548, C-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This MMP16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 519-548 amino acids from the C-terminal region of human MMP16.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    MMP16 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

    有效期

    6 months
  • Wu, Ma, Shan, Zhou, Li: "High expression of matrix metalloproteinases 16 is associated with the aggressive malignant behavior and poor survival outcome in colorectal carcinoma." in: Scientific reports, Vol. 7, pp. 46531, (2017) (PubMed).

    Shen, Wang, Yu, Zhang, Qin: "MMP16 promotes tumor metastasis and indicates poor prognosis in hepatocellular carcinoma." in: Oncotarget, Vol. 8, Issue 42, pp. 72197-72204, (2017) (PubMed).

  • 抗原

    MMP16 (Matrix Metallopeptidase 16 (Membrane-inserted) (MMP16))

    别名

    MMP16

    背景

    Endopeptidase that degrades various components of the extracellular matrix, such as collagen type III and fibronectin. Activates progelatinase A. Involved in the matrix remodeling of blood vessels. Isoform short cleaves fibronectin and also collagen type III, but at lower rate. It has no effect on type I, II, IV and V collagen. However, upon interaction with CSPG4, it may be involved in degradation and invasion of type I collagen by melanoma cells.

    分子量

    69521

    基因ID

    4325

    NCBI登录号

    NP_005932

    UniProt

    P51512
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