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MMP2 抗体 (AA 303-331)

This anti-MMP2 antibody is a 兔 多克隆 antibody detecting MMP2 in WB. Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN657616
发货至: 中国

Quick Overview for MMP2 抗体 (AA 303-331) (ABIN657616)

抗原

See all MMP2 抗体
MMP2 (Matrix Metalloproteinase 2 (MMP2))

适用

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宿主

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克隆类型

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多克隆

标记

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This MMP2 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB33605
  • 抗原表位

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    AA 303-331

    预测反应

    C, M, Rb, Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This MMP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 303-331 amino acids from the Central region of human MMP2.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    MMP2 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

    有效期

    6 months
  • Chen, Liu, Gao, Hui, Yang, Zhang, Xu, Tian, Fan: "Preliminary evaluation for Bit1 as a potential biomarker for squamous cell carcinoma and adenocarcinoma of esophagus." in: Tumour biology, Vol. 39, Issue 5, pp. 1010428317708270, (2017) (PubMed).

    Dai, Duan, Duan, Zhou, He, Tu, Shen: "Down-regulation of TCF21 by hypermethylation induces cell proliferation, migration and invasion in colorectal cancer." in: Biochemical and biophysical research communications, (2015) (PubMed).

    Shi, Shang, Pan, Wang, Jiang, Hao, Zhang, Cai, Xu, Zhan, Wang: "Calreticulin promotes migration and invasion of esophageal cancer cells by upregulating neuropilin-1 expression via STAT5A." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 20, Issue 23, pp. 6153-62, (2014) (PubMed).

  • 抗原

    MMP2 (Matrix Metalloproteinase 2 (MMP2))

    别名

    MMP2

    背景

    Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene.

    分子量

    73882

    基因ID

    4313

    NCBI登录号

    NP_001121363, NP_004521

    UniProt

    P08253

    途径

    Activation of Innate immune Response
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