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Estrogen Receptor alpha 抗体 (AA 246-273)

Name: Estrogen Receptor alpha 抗体 (AA 246-273)
SKU: ABIN657470
Availability: OutOfStock

This anti-Estrogen Receptor alpha antibody is a 兔多克隆 antibody detecting Estrogen Receptor alpha in WB, IF 和 IHC (p). Suitable for 人和小鼠. This Primary Antibody has been cited in 4+ publications.

All lanes : Anti-ESR1/ER Antibody (Center) at 1:2000 dilution Lane 1: MCF-7 whole cell lysate Lane 2: T47D whole cell lysate Lane 3: ZR-75-1 whole cell lysate Lysates/proteins at 20 μg per lane. (Estrogen Receptor alpha 抗体 (AA 246-273))

Immunohistochemical analysis of (ABIN657470 and ABIN2846498) on paraffin-embedded Human breast carcinoma tissue. (Estrogen Receptor alpha 抗体 (AA 246-273))

IHC (p)

Confocal immunofluorescent analysis of ESR1/ER Antibody (Center) (ABIN657470 and ABIN2846498) with ZR-75-1 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). (Estrogen Receptor alpha 抗体 (AA 246-273))

Anti-ESR1/ER Antibody (Center) at 1:2000 dilution + Mouse testis whole cell lysate Lysates/proteins at 20 μg per lane. (Estrogen Receptor alpha 抗体 (AA 246-273))

Immunohistochemical analysis of (ABIN657470 and ABIN2846498) on paraffin-embedded Human uterus tissue. (Estrogen Receptor alpha 抗体 (AA 246-273))

IHC (p)

5 images

(4 references)

产品编号 ABIN657470

发货至: 中国

Datasheet as PDF

Quick Overview for Estrogen Receptor alpha 抗体 (AA 246-273) (ABIN657470)

抗原

See all Estrogen Receptor alpha (ESR1) 抗体

Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

适用

人, 小鼠

宿主

兔

克隆类型

多克隆

标记

This Estrogen Receptor alpha antibody is un-conjugated

应用范围

Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB33807

Discover our top product ESR1 Primary Antibody

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AA 246-273

预测反应

B, Hs, Pig, Rat

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This ESR1/ER antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 246-273 amino acids from the Central region of human ESR1/ER.

亚型

Ig Fraction
anti-Estrogen Receptor 1 (ESR1) (AA 129-312) antibody
ESR1 适用: 人 IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal ESR1-3557 unconjugated

anti-Estrogen Receptor 1 (ESR1) antibody
ESR1 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal ESR1-1904 unconjugated

anti-Estrogen Receptor 1 (ESR1) (AA 2-185) antibody
ESR1 适用: 人, 大鼠 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 6A6E8 unconjugated

anti-Estrogen Receptor 1 (ESR1) (pSer167) antibody
ESR1 适用: 人, 大鼠 ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Estrogen Receptor 1 (ESR1) (AA 2-185) antibody
ESR1 适用: 人 WB, IHC, FACS, StM 宿主: 小鼠 Monoclonal ER506 unconjugated

anti-Estrogen Receptor 1 (ESR1) (C-Term) antibody
ESR1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Estrogen Receptor 1 (ESR1) (AA 246-273) antibody
ESR1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Estrogen Receptor 1 (ESR1) (AA 331-360) antibody
ESR1 适用: 人, 大鼠 WB, ELISA, FACS, IF (cc) 宿主: 兔 Polyclonal unconjugated

anti-Estrogen Receptor 1 (ESR1) (pSer118) antibody
ESR1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Estrogen Receptor 1 (ESR1) (AA 233-483) antibody
ESR1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

IF: 1:10~50. WB: 1:2000. WB: 1:2000. IHC-P: 1:100. IHC-P: 1:100

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

ESR1/ER Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

有效期

6 months
Zhu, Xu, Rashedi, Pavone, Kim, Woodruff, Burdette: "Human fallopian tube epithelium co-culture with murine ovarian follicles reveals crosstalk in the reproductive cycle." in: Molecular human reproduction, Vol. 22, Issue 11, pp. 756-767, (2018) (PubMed).

Wang, Zhou, Guan, Yu, Wang: "β-Estradiol antagonizes the inhibitory effects of caffeine in BMMSCs via the ERβ-mediated cAMP-dependent PKA pathway." in: Toxicology, Vol. 394, pp. 1-10, (2018) (PubMed).

Arslan, Yu, Burdette, Pavone, Hope, Woodruff, Kim: "Novel three dimensional human endocervix cultures respond to 28-day hormone treatment." in: Endocrinology, Vol. 156, Issue 4, pp. 1602-9, (2015) (PubMed).

Bi, Yang, Yu, Zhao, Zhao, He, Jing, Wang, Huang: "Pregnancy serum facilitates hepatitis E virus replication in vitro." in: The Journal of general virology, Vol. 96, Issue Pt 5, pp. 1055-61, (2015) (PubMed).
抗原

Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

别名

ESR1/ER

背景

This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.

分子量

66216

基因ID

2099

NCBI登录号

NP_000116, NP_001116212, NP_001116213, NP_001116214

UniProt

P03372

途径

Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly