JARID2 抗体
Quick Overview for JARID2 抗体 (ABIN6572030)
抗原
See all JARID2 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein of human JARID2
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- JARID2 (Jumonji, AT Rich Interactive Domain 2 (JARID2))
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别名
- JARID2
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背景
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Synonyms: JARD2,JARD2,JARID2,JMJ,Jumonji AT rich interactive domain 2 ,Jumonji homolog,Jumonji like protein,Jumonji protein,Jumonji/ARID domain containing protein 2,Jumonji/ARID domain-containing protein 2,Protein Jumonji
Background: This gene encodes a Jumonji- and AT-rich interaction domain (ARID)-domain-containing protein. The encoded protein is a DNA-binding protein that functions as a transcriptional repressor. This protein interacts with the Polycomb repressive complex 2 (PRC2) which plays an essential role in regulating gene expression during embryonic development. This protein facilitates the recruitment of the PRC2 complex to target genes. Alternate splicing results in multiple transcript variants. Mutations in this gene are associated with chronic myeloid malignancies.
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分子量
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Observed_MW: 139kDa
Calculated_MW: 106kDa/119kDa/138kDa
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基因ID
- 3720
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UniProt
- Q92833
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途径
- Chromatin Binding
抗原
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