EPH Receptor B2 抗体
Quick Overview for EPH Receptor B2 抗体 (ABIN6572022)
抗原
See all EPH Receptor B2 (EPHB2) 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein of human EPHB2
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- EPH Receptor B2 (EPHB2)
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别名
- EPHB2
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背景
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Synonyms: cek5,Developmentally regulated EPH related tyrosine kinase,DRT,EK5,ELK related protein tyrosine kinase,Eph receptor B2,EPH tyrosine kinase 3,EPH-like kinase 5,EPHB2,EPHB2,Ephrin type B receptor 2,Ephrin type-B receptor 2,EPHT 3,ERK,ETECK,hEK5,Nuk,Prkm 5,Receptor protein tyrosine kinase HEK 5,Renal carcinoma antigen NY-REN-47,Sek 3,Tyro 5,Tyrosine protein kinase receptor CEK 5,Tyrosine protein kinase receptor EPH 3,Tyrosine protein kinase receptor QEK 5,Tyrosine-protein kinase receptor EPH-3,Tyrosine-protein kinase TYRO5
Background: This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a transmembrane region and an intracellular kinase domain. They bind ligands called ephrins and are involved in diverse cellular processes including motility, division, and differentiation. A distinguishing characteristic of Eph-ephrin signaling is that both receptors and ligands are competent to transduce a signaling cascade, resulting in bidirectional signaling. This protein belongs to a subgroup of the Eph receptors called EphB. Proteins of this subgroup are distinguished from other members of the family by sequence homology and preferential binding affinity for membrane-bound ephrin-B ligands. Allelic variants are associated with prostate and brain cancer susceptibility. Alternative splicing results in multiple transcript variants.
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分子量
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Observed_MW: 117kDa
Calculated_MW: 109kDa/110kDa/117kDa
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基因ID
- 2048
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UniProt
- P29323
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途径
- RTK signaling, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins
抗原
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