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Androgen Receptor 抗体 (Center)

AR 适用: 人 WB 宿主: 兔 Polyclonal RB32967 unconjugated
产品编号 ABIN656982
发货至: 中国
  • 抗原 See all Androgen Receptor (AR) 抗体
    Androgen Receptor (AR)
    抗原表位
    • 21
    • 19
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    • 15
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    • 12
    • 8
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    • 1
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    • 1
    • 1
    • 1
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    • 1
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    AA 282-309, Center
    适用
    • 296
    • 91
    • 86
    • 29
    • 17
    • 17
    • 15
    • 12
    • 8
    • 4
    • 4
    • 3
    • 1
    宿主
    • 251
    • 48
    • 1
    • 1
    • 1
    克隆类型
    • 243
    • 57
    多克隆
    标记
    • 109
    • 27
    • 14
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    • 13
    • 13
    • 13
    • 13
    • 12
    • 12
    • 7
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    • 7
    • 7
    • 7
    • 7
    • 7
    • 2
    • 2
    • 2
    • 2
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    • 1
    This Androgen Receptor antibody is un-conjugated
    应用范围
    • 177
    • 87
    • 65
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    • 37
    • 28
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    • 11
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    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    特异性
    This AR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 281-309 amino acids from the Central region of human AR.
    预测反应
    Monkey
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This AR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 282-309 AA from the Central region of human AR.
    克隆位点
    RB32967
    亚型
    Ig Fraction
    Top Product
    Discover our top product AR Primary Antibody
  • 应用备注
    WB = 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.33 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    AR Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
    有效期
    6 months
  • 抗原
    Androgen Receptor (AR)
    别名
    AR (AR 产品)
    别名
    AIS antibody, DHTR antibody, HUMARA antibody, HYSP1 antibody, KD antibody, NR3C4 antibody, SBMA antibody, SMAX1 antibody, TFM antibody, AW320017 antibody, Tfm antibody, Andr antibody, AR antibody, androgen receptor antibody, AR antibody, Ar antibody, ar antibody
    背景
    The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq].
    Synonyms: Androgen receptor,AR,DHTR, NR3C4
    分子量
    98989 DA
    基因ID
    367
    NCBI登录号
    NP_001011645, NP_000035
    UniProt
    P10275
    途径
    Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding
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