KREMEN2 抗体 (AA 248-276)
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Quick Overview for KREMEN2 抗体 (AA 248-276) (ABIN656978)
抗原
See all KREMEN2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 248-276
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This KREMEN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248-276 amino acids from the Central region of human KREMEN2.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- KREMEN2 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
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有效期
- 6 months
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- KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))
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别名
- KREMEN2
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背景
- This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.
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分子量
- 48849
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基因ID
- 79412
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NCBI登录号
- NP_001240654, NP_001240655, NP_078783, NP_757384
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UniProt
- Q8NCW0
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途径
- WNT signaling
抗原
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