PLAU 抗体
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北京 101111
Quick Overview for PLAU 抗体 (ABIN6569163)
抗原
See all PLAU 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein of human PLAU
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- PLAU (Plasminogen Activator, Urokinase (PLAU))
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别名
- PLAU
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背景
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Synonyms: ATF,ATF uPA,BDPLT5,Plasminogen activator,Plasminogen activator urinary,Plasminogen activator urokinase,PLAU,QPD,u PA,U plasminogen activator,u-PA,U-plasminogen activator,uPA,URK,UROK,Urokinase plasminogen activator,Urokinase type plasminogen activator,Urokinase type plasminogen activator precursor,Urokinase-type plasminogen activator chain B
Background: This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
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分子量
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Observed_MW: 45kDa
Calculated_MW: 46kDa/48kDa
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基因ID
- 5328
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UniProt
- P00749
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途径
- Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration
抗原
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