IDE 抗体
Quick Overview for IDE 抗体 (ABIN6568815)
抗原
See all IDE 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein of human IDE
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亚型
- IgG
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anti-Insulin-Degrading Enzyme (IDE) (AA 491-590) antibody
IDE 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Degrading Enzyme (IDE) (AA 753-973) antibodyIDE 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Degrading Enzyme (IDE) (AA 1-250) antibodyIDE 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Degrading Enzyme (IDE) antibodyIDE 适用: 人 WB, IHC (p), IF 宿主: 小鼠 Monoclonal 1H4 unconjugated
anti-Insulin-Degrading Enzyme (IDE) (AA 920-1019) antibodyIDE 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Insulin-Degrading Enzyme (IDE) (Internal Region) antibodyVerified IDE 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Insulin-Degrading Enzyme (IDE) (N-Term) antibodyIDE 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Degrading Enzyme (IDE) antibodyIDE 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Degrading Enzyme (IDE) (AA 501-800) antibodyIDE 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000 IF 1:10 - 1:100
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- IDE (Insulin-Degrading Enzyme (IDE))
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别名
- IDE
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背景
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Synonyms: Abeta-degrading protease,FLJ35968,Ide,IDE,Insulin protease,Insulin-degrading enzyme,Insulinase,Insulysin,OTTHUMP00000020097
Background: This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases. This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but have not been experimentally verified.
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分子量
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Observed_MW: 118kDa
Calculated_MW: 54kDa/117kDa
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基因ID
- 3416
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UniProt
- P14735
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途径
- SARS-CoV-2 Protein Interactome
抗原
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