NTAN1 抗体
Quick Overview for NTAN1 抗体 (ABIN6568757)
抗原
See all NTAN1 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein of human NTAN1
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亚型
- IgG
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anti-N-terminal Asparagine Amidase (NTAN1) (AA 219-310) antibody
NTAN1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-N-terminal Asparagine Amidase (NTAN1) antibodyNTAN1 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-N-terminal Asparagine Amidase (NTAN1) (AA 1-310) antibodyNTAN1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-N-terminal Asparagine Amidase (NTAN1) (AA 1-310) antibodyNTAN1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:200 - 1:2000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- NTAN1 (N-terminal Asparagine Amidase (NTAN1))
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别名
- NTAN1
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背景
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Synonyms: N terminal Asn amidase,N terminal asparagine amidase ,N terminal asparagine amidohydrolase,NTN-amidase,PNAA ,PNAD ,Protein N-terminal Asn amidase,Protein N-terminal asparagine amidase,Protein N-terminal asparagine amidohydrolase,Protein NH2-terminal asparagine amidohydrolase,Protein NH2-terminal asparagine deamidase,Protein NTN-amidase
Background: The protein encoded by this gene functions in a step-wise process of protein degradation through the N-end rule pathway. This protein acts as a tertiary destabilizing enzyme that deamidates N-terminal L-Asn residues on proteins to produce N-terminal L-Asp. L-Asp substrates are subsequently conjugated to L-Arg, which is recognized by specific E3 ubiquitin ligases and targeted to the proteasome. Pseudogenes of this gene are located on the long arms of chromosomes 8, 10 and 12. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
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分子量
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Observed_MW: 35kDa
Calculated_MW: 34kDa
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基因ID
- 123803
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UniProt
- Q96AB6
抗原
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