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NTAN1 抗体 (N-Term)

NTAN1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7469243
发货至: 中国
  • 抗原 See all NTAN1 抗体
    NTAN1 (N-terminal Asparagine Amidase (NTAN1))
    抗原表位
    • 8
    • 7
    • 6
    • 4
    • 2
    N-Term
    适用
    • 29
    • 9
    • 1
    宿主
    • 28
    • 1
    克隆类型
    • 29
    多克隆
    标记
    • 9
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NTAN1 antibody is un-conjugated
    应用范围
    • 17
    • 16
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human NTAN1. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product NTAN1 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: 293T

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    NTAN1 (N-terminal Asparagine Amidase (NTAN1))
    别名
    NTAN1 (NTAN1 产品)
    别名
    PNAA antibody, PNAD antibody, N-terminal Asn amidase antibody, N-terminal asparagine amidase antibody, Ntan1 antibody, NTAN1 antibody
    背景

    Synonyms: N-terminal asparagine amidase , PNAA , PNAD

    Background: Side-chain deamidation of N-terminal asparagine residues to aspartate. Required for the ubiquitin-dependent turnover of intracellular proteins that initiate with Met-Asn. These proteins are acetylated on the retained initiator methionine and can subsequently be modified by the removal of N-acetyl methionine by acylaminoacid hydrolase (AAH). Conversion of the resulting N-terminal asparagine to aspartate by PNAD renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. This enzyme does not act on substrates with internal or C-terminal asparagines and does not act on glutamine residues in any position.

    分子量
    35 kDa
    基因ID
    123803
    UniProt
    Q96AB6
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