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PPARA 抗体 (AA 153-181)

This anti-PPARA antibody is a 兔 多克隆 antibody detecting PPARA in WB 和 FACS. Suitable for 小鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN656834
发货至: 中国

Quick Overview for PPARA 抗体 (AA 153-181) (ABIN656834)

抗原

See all PPARA 抗体
PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This PPARA antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS)

克隆位点

RB21340
  • 抗原表位

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    AA 153-181

    预测反应

    Rat, X

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This PPARA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 153-181 amino acids from the Central region of human PPARA.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    PPARA Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

    有效期

    6 months
  • Spruiell, Richardson, Cullen, Awumey, Gonzalez, Gyamfi: "Role of pregnane X receptor in obesity and glucose homeostasis in male mice." in: The Journal of biological chemistry, Vol. 289, Issue 6, pp. 3244-61, (2014) (PubMed).

  • 抗原

    PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))

    别名

    PPARA

    背景

    Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers, this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined.

    分子量

    52225

    基因ID

    5465

    NCBI登录号

    NP_001001928, NP_005027

    UniProt

    Q07869

    途径

    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Hepatitis C
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