PPARA 抗体 (AA 153-181)
Quick Overview for PPARA 抗体 (AA 153-181) (ABIN656834)
抗原
See all PPARA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 153-181
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预测反应
- Rat, X
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This PPARA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 153-181 amino acids from the Central region of human PPARA.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. FC: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- PPARA Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
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有效期
- 6 months
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: "Role of pregnane X receptor in obesity and glucose homeostasis in male mice." in: The Journal of biological chemistry, Vol. 289, Issue 6, pp. 3244-61, (2014) (PubMed).
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: "Role of pregnane X receptor in obesity and glucose homeostasis in male mice." in: The Journal of biological chemistry, Vol. 289, Issue 6, pp. 3244-61, (2014) (PubMed).
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- PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))
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别名
- PPARA
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背景
- Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers, this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined.
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分子量
- 52225
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基因ID
- 5465
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NCBI登录号
- NP_001001928, NP_005027
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UniProt
- Q07869
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途径
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Hepatitis C
抗原
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