Dynamitin 抗体 (AA 192-219)
Quick Overview for Dynamitin 抗体 (AA 192-219) (ABIN656819)
抗原
See all Dynamitin (DCTN2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 192-219
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预测反应
- B, M, Rat
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This DCTN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 192-219 amino acids from the Central region of human DCTN2.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. IHC-P: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- DCTN2 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
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有效期
- 6 months
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- Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))
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别名
- DCTN2
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背景
- This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place.
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分子量
- 44231
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基因ID
- 10540
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NCBI登录号
- NP_001248341, NP_001248342, NP_006391
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UniProt
- Q13561
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途径
- M Phase, Ribonucleoprotein Complex Subunit Organization
抗原
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