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MANF 抗体

MANF 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6567918
发货至: 中国
  • 抗原 See all MANF 抗体
    MANF (Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF))
    适用
    • 44
    • 21
    • 19
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 35
    • 8
    • 1
    克隆类型
    • 38
    • 6
    多克隆
    标记
    • 30
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
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    This MANF antibody is un-conjugated
    应用范围
    • 36
    • 20
    • 11
    • 7
    • 6
    • 5
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein of human MANF
    亚型
    IgG
    Top Product
    Discover our top product MANF Primary Antibody
  • 应用备注
    WB 1:500 - 1:2000 IHC 1:50 - 1:200
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    MANF (Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF))
    别名
    MANF (MANF 产品)
    背景

    Synonyms: Arginine rich mutated in early stage tumors,Arginine rich protein,Arginine-rich protein,ARMET,ARMET protein,ARP,Manf,MANF,Mesencephalic astrocyte derived neurotrophic factor,Mesencephalic astrocyte-derived neurotrophic factor,MGC142148,MGC142150,Protein ARMET

    Background: The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and results in cell proliferation. Activity of this protein is important in promoting the survival of dopaminergic neurons. The presence of polymorphisms in the N-terminal arginine-rich region, including a specific mutation that changes an ATG start codon to AGG, have been reported in a variety of solid tumors, however, these polymorphisms were later shown to exist in normal tissues and are thus no longer thought to be tumor-related.

    分子量

    Observed_MW: 16kDa

    Calculated_MW: 20kDa

    基因ID
    7873
    UniProt
    P55145
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