GCN2 抗体
Quick Overview for GCN2 抗体 (ABIN6567595)
抗原
See all GCN2 (EIF2AK4) 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein of human EIF2AK4
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- GCN2 (EIF2AK4) (Eukaryotic Translation Initiation Factor 2 alpha Kinase 4 (EIF2AK4))
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别名
- EIF2AK4
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背景
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Synonyms: E2AK4,Eif2ak4,Eukaryotic Translation Initiation Factor 2 alpha kinase 4,Eukaryotic translation initiation factor 2-alpha kinase 4,GCN2,GCN2 eIF2alpha kinase,GCN2 like protein,GCN2-like protein,KIAA1338,MGCN2
Background: This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2.
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分子量
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Observed_MW: 187kDa
Calculated_MW: 69kDa/183kDa/186kDa
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基因ID
- 440275
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UniProt
- Q9P2K8
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途径
- ER-Nucleus Signaling, Hepatitis C
抗原
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