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ALDH2 抗体

This anti-ALDH2 antibody is a 兔 多克隆 antibody detecting ALDH2 in WB, IHC 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6567396
发货至: 中国

Quick Overview for ALDH2 抗体 (ABIN6567396)

抗原

See all ALDH2 抗体
ALDH2 (Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2))

适用

  • 79
  • 25
  • 24
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 62
  • 18
  • 2

克隆类型

  • 58
  • 24
多克隆

标记

  • 49
  • 9
  • 3
  • 3
  • 3
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  • 2
  • 2
  • 2
  • 2
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  • 2
This ALDH2 antibody is un-conjugated

应用范围

  • 68
  • 40
  • 34
  • 19
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  • 11
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  • 3
  • 2
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 纯化方法

    Affinity purification

    免疫原

    Recombinant protein of human ALDH2

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    ALDH2 (Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2))

    别名

    ALDH2

    背景

    Synonyms: Acetaldehyde dehydrogenase 2,Aldehyde dehydrogenase 2 family (mitochondrial),Aldehyde dehydrogenase 2 family,Aldehyde dehydrogenase mitochondrial,Aldehyde dehydrogenase,mitochondrial,ALDH 2,ALDH class 2,ALDH E2,ALDH-E2,Aldh2,ALDH2,ALDHI,ALDM,Liver mitochondrial ALDH,MGC1806,Mitochondrial aldehyde dehydrogenase 2,MS767,Nucleus encoded mitochondrial aldehyde dehydrogenase 2

    Background: This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50 % of East Asians have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among East Asians than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

    分子量

    Observed_MW: 53kDa

    Calculated_MW: 50kDa/56kDa

    基因ID

    217

    UniProt

    P05091
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