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LIN7C 抗体 (C-Term)

This anti-LIN7C antibody is a 兔 多克隆 antibody detecting LIN7C in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN656734
发货至: 中国

Quick Overview for LIN7C 抗体 (C-Term) (ABIN656734)

抗原

See all LIN7C 抗体
LIN7C (Lin-7 Homolog C (LIN7C))

适用

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宿主

  • 31

克隆类型

  • 31
多克隆

标记

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This LIN7C antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB32322
  • 抗原表位

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    AA 168-197, C-Term

    预测反应

    B, M, Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This LIN7C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-197 amino acids from the C-terminal region of human LIN7C.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    LIN7C Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

    有效期

    6 months
  • 抗原

    LIN7C (Lin-7 Homolog C (LIN7C))

    别名

    LIN7C

    背景

    LIN7C plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.

    分子量

    21834

    基因ID

    55327

    NCBI登录号

    NP_060832

    UniProt

    Q9NUP9

    途径

    Synaptic Membrane
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