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ACTN1 抗体

ACTN1 适用: 人, 小鼠, 猴 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6567190
发货至: 中国
  • 抗原 See all ACTN1 抗体
    ACTN1 (Actinin, alpha 1 (ACTN1))
    适用
    • 57
    • 21
    • 18
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    人, 小鼠, 猴
    宿主
    • 48
    • 9
    • 1
    克隆类型
    • 50
    • 8
    多克隆
    标记
    • 33
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ACTN1 antibody is un-conjugated
    应用范围
    • 40
    • 26
    • 19
    • 17
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human ACTN1 (NP_001123477.1).
    亚型
    IgG
    Top Product
    Discover our top product ACTN1 Primary Antibody
  • 应用备注
    WB 1:500-1:2000 IHC 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    ACTN1 (Actinin, alpha 1 (ACTN1))
    别名
    ACTN1 (ACTN1 产品)
    别名
    ACTN1 antibody, actinin antibody, BDPLT15 antibody, 3110023F10Rik antibody, Actn1a antibody, actinin alpha 1 antibody, actinin, alpha 1 antibody, actinin alpha 1 L homeolog antibody, ACTN1 antibody, actn1 antibody, Actn1 antibody, actn1.L antibody
    背景
    Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.
    分子量

    Observed_MW: 110kDa

    Calculated_MW: 102kDa/103kDa/105kDa/107kDa

    基因ID
    87
    UniProt
    P12814
    途径
    Cell-Cell Junction Organization
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